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In a randomized clinical trial , adults with obesity or overweight (but without diabetes) who took Saxenda experienced an average weight loss of 6.4% in 68 weeks (about a year and a half)

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Led by researchers at University College London (UCL), University College London Hospitals and Homerton University Hospital, the BARI-STEP trial evaluated the efficacy and safety of semaglutide 2.4 mg once weekly in patients who had undergone Roux-en-Y gastric bypass or sleeve gastrectomy at least one year previously but had lost less than 20% of their body weight after surgery

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