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Its cost can be quite high, especially without insurance

This represents significant savings compared to brand-name Ozempic copays and out-of-pocket costs

Berberine can interact with cytochrome P450 enzymes and P-glycoprotein, which affects the metabolism of certain drugs, but metformins main elimination route is renal excretion rather than hepatic metabolism, so direct interaction is less likely

Additionally, AIE technology offers a novel strategy for highlighting tumor tissues through specific binding between AIEgens and specific biomacromolecules in tumor cells, triggering restriction of intramolecular motions to inducing emission