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Mediterranean diet and SARS-COV-2 infection: is there any association

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Overexpression of SIRT6 inhibits the ubiquitin proteasome system and promotes HIF-1 accumulation, upregulating the expression of VEGF, angiopoietins1 (Ang1), Ang2, and platelet-derived growth factor-BB (PDGF-BB), consequently enhancing migration, invasion, and proliferation of human umbilical vein endothelial cells (47, 48)

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