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Current research on allulose and GLP-1 secretion is limited, with most studies conducted in animal models or small human trials

Commenters stated that the limited claims data (less than 1 year) does not accurately reflect the costs of providing SAINT and that CMS should not use the small dataset that is available for determining the rates for CY 2026

Histidine is a precursor of histamine, a compound released by the immune system cells during an allergic reaction

Although the exact mechanism of how this is achieved remains unknown, the authors emphasize the potential ability of GLP-1 to protect the central nervous system [57]