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Cederbaum (2012) Alcohol metabolism is regulated by the nutritional state, the concentration of alcohol,specific isoforms of alcohol dehyrogenase, need to remove acetaldehyde and regenerate NAD and induction of CYP2E1
Oxygen consumption in isolated mitochondria from livers in the presence of (A) 1 mM succinate plus 1 M rotenone or (B) 200 M TMPD plus 2 mM ascorbate
Maintenance (periodic): once youre steady, space sessions out and use add-ins only when helpful
They will examine all pregnancy complications, cases of severe illness, infant deaths and other SAEs to decide if the study should be continued, based on the predecided stopping rules
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