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Interestingly, the analysis of the tumors by immunoblot revealed decreased levels of galectin-1 and a subsequent elevated levels of granzyme B in tumors that were treated with the combination of sertraline and irradiation ( p = 0.047, p = 0.016, respectively) (Fig

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Likewise, cytotoxicity assays of de-epoxy derivatives of DON (named DOM-1) and NIV showed IC 50 values that were 52 and 51 times higher than the parent mycotoxins, respectively (Eriksen and Pettersson, 2004)