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The drug mimics a natural hormone called GLP-1 (glucagon-like peptide-1), which helps regulate blood sugar levels and appetite

An unexpected finding in our studies was the loss of improved lipid tolerance in Dpp4 EC/ mice, with or without coadministration of sitagliptin, following BMT, implying an interaction between bone marrowderived cells and the metabolic actions emanating from the reduction of DPP-4 activity in endothelial cells

These medications stimulate the pancreas to release insulin in response to meals, helping patients achieve stable glucose levels

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