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The limitations of the study are the small number of enrolled patients, the lack of a placebo control, and the insufficient accuracy of the microbiota analysis

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Effect of cannabis in combination with antidepressant drugs The immobility time in mice co-administered with fluoxetine (20 mg/kg, s.c.) and cannabis (5 mg/kg, s.c.) was significantly increased compared with the vehicle control group as well as with the cannabis only-treated group

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17,18 NAD + has been detected in the nucleus and in almost all cytoplasmic organelles

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Overall Cardiometabolic Impact: Across both metabolic groups, yerba mate demonstrated cardiometabolic protective potentialimproving blood pressure, lowering inflammation, supporting lipid metabolism, and modulating key metabolic and gastrointestinal hormones

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