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Studies typically begin with a low titration phase to allow receptor adaptation (e.g., 2mg or 4mg weekly), increasing slowly over months to reach the target maintenance dose (up to 12mg in some trials, though this product contains 20mg total)

She said advocacy groups are working with the CMS to provide evidence and rationale to update that coverage determination. TRICARE, which covers military service members, families and retirees, had been covering the drugs but is pulling back

Your healthcare provider will determine the appropriate monitoring schedule based on your individual response to treatment