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Semaglutide GLP-1 is one such drug that belongs to the class of GLP-1 receptor agonists

10.1016/S0092-8674(00)00205-1 Cell 25 CappellariM.BoviP.MorettoG

The distinct contributions of each receptor system - GLP-1-mediated improvements in insulin sensitivity and appetite regulation, GIP-mediated enhancement of insulin secretion and adipose tissue function, and glucagon-mediated direct hepatic metabolic modulation and increased energy expenditure - create synergistic benefits when engaged through dual or triple agonist formulations