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Description

Obesity 33 , 225237 (2025)

Improper reconstitution or storage can degrade the peptide, potentially reducing efficacy (requiring higher doses and more side effects) or introducing contaminants

10.1038/s41586-022-04898-5 137 DemeneixB

IR occurs when target tissues, such as skeletal muscle, liver, and adipose tissue, exhibit reduced sensitivity to insulin, impairing glucose uptake and utilization [156, 157]