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In fact, approaches to enhance postprandial accommodation have been associated with reduced symptoms of functional dyspepsia, for example, by using the serotonergic 5-HT 1A agonist, buspirone, or by using acotiamide, an antagonist of acetylcholinesterase and antagonist of presynaptic M 1 and M 2 muscarinic receptors

The EMA also said that marketing authorisation holders must ensure that any promotion of these medicines have been approved by regulatory authorities, adding that claims made by companies in the context of such activities should align with rational medicine use and public health goals

Most patients complete their dose titration within 16 to 20 weeks, gradually moving from 0.25 mg up to their target dose

Brain Res 2002;940:102-4.PubMed 49