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Patient safety considerations include the potential for injection site reactions when administering multiple subcutaneous injections, particularly if proper site rotation is not maintained

Kuo WP, Tigges JC, Toxavidis V, Ghiran I

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In these reports, oral semaglutide showed a higher signal strength for diabetic retinopathy (= 8, 95% CI: 18.99, 9.4938.02) and vitreous hemorrhage (= 4, 95% CI: 11.70, 4.3931.21), though the frequencies were not high