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The GABA-A receptor is a Cl channel that, in response to GABA binding induces an inward flux of Cl into the neuron

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In this context, Figure 1 illustrates how GLP-1 RAs activate the GLP-1R, subsequently initiating key intracellular signaling pathways such as Epac/PI3K/Akt, cAMP/PKA, and ERK/MAPK

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