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If you have a history of severe allergies or chemical sensitivities, starting with a very low dose and monitoring your breathing is a practical approach

[DOI] [PubMed] [Google Scholar] [21].Castegna A, Aksenov M, Aksenova M, Thongboonkerd V, Klein JB, Pierce WM, Booze R, Markesbery WR, Butterfield DA

The subsequent treatment of 28 days of saffron (30 mg/kg) or crocin (15 or 30 mg/kg) or saline was performed on the postnatal days 3033 on male offspring