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The SELECT cardiovascular outcomes trial (N=17,604), published in NEJM 2023 (DOI: 10.1056/NEJMoa2307563), demonstrated a 20% reduction in major adverse cardiovascular events (MACE) -- the composite of cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke -- in overweight or obese adults without diabetes

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10.1056/NEJMoa1603827 [DOI] [PMC free article] [PubMed] [Google Scholar] 101.Pratley RE, Aroda VR, Lingvay I, Ludemann J, Andreassen C, Navarria A, et al

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