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Although GLP-1 medications are highly effective for obesity treatment, disregarding sexual health and desire as an essential consideration in initiation of GLP-1 agonist therapy presents a serious concern
GLP-1 Agonist plus IL-17 Inhibition in Obese Psoriatic Arthritis Save Lilly announced the topline results from its phase 3b "TOGETHER PsA" trial, showing that the combination use of ixekizumab (Taltz) and tirzepatide (Zepbound) was superior to IXE alone, yielding both significant weight loss and ACR50 disease control in adults with active psoriatic arthritis (PsA)
The difference is mechanism: tirzepatide activates both the GIP and GLP-1 receptors, while semaglutide targets GLP-1 alone
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