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These are unstable molecules created due to stress , illness, and environmental pollutants

Hecker M

Additionally, the excessive reduction of cystine to cysteine consumes large amounts of NADPH, a critical cofactor for maintaining cellular reducing power (Chandel, 2021) (Figure 8)

Graphical Abstract Similar content being viewed by others Introduction The tight junction-connected, non-fenestrated brain capillary endothelial cells in cross-talk with the neighboring pericytes and astroglial endfeet create the dynamic anatomical and functional unit called as bloodbrain barrier (BBB) [1]