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Oxid Med Cell Longev (2018) 2018:9156285

Thyroid glandular provides tissue-specific factors from thyroid tissue including naturally occurring thyroid peptides, thyroid proteins (including thyroglobulin), co-factors, and enzymatic components involved in normal thyroid hormone synthesis and cellular thyroid function.* The thyroid gland is responsible for the synthesis and secretion of thyroxine (T4) and triiodothyronine (T3) the primary hormones regulating metabolic rate, normal energy production, body temperature, heart rate, and virtually every organ system's metabolic activity

The structure was solved by molecular replacement with coordinates and phases derived from the FAT-LD2 complex (PDB ID 1OW8 24 ) as an initial search model and then refined in PHENIX 56