Its ability to enhance neuronal survival, promote neurogenesis, keep memory, and facilitate memory synaptogenesis contributes to slowing down or reversing the cognitive decline associated with this devastating condition
FIGURE 9 Summary and conclusions: Glutathione and early (premature) inflammaging Chronic inflammatory diseases especially those compromising the lower respiratory system (chronic obstructive pulmonary disease, lower respiratory infections, cystic fibrosis, idiopathic pulmonary fibrosis, acute respiratory distress syndrome), diseases compromising the cardiovascular system (atherosclerosis, ischemic heart disease, stroke, and others), many other systemic inflammatory diseases like diabetes (274, 275)
Our conclusions regarding ASCT2-specific causality should be viewed as pharmacological observations that warrant further validation using genetic approaches for gene silencing, such as siRNA- or CRISPR-based methods to definitively confirm the specificity of these findings
Bales CW, Kraus WE