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PMID: 21561431

A single change in the aptamer of the Lactiplantibacillus plantarum rib operon riboswitch severely impairs its regulatory activity and leads to a vitamin B2- overproducing phenotype

The selection of peptide segments can be based on an understanding of the structure and function of the target molecule or obtained through screening large peptide libraries to identify segments with specific binding properties

Compared to normal joints, the extracellular matrix of RAM of RA boasts a higher-content of a series of inflammatory factors, matrix metalloproteinases (MMP), many kinds of RONS, H + , while simultaneously exhibiting a lower concentration of oxygen [7]