glp-1 incretin Figure 4 from Two hormones and GIP: comparison of their actions in insulin secretion and β cell preservation GLP-1 and GIP in Type

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Weight reduction and reduced adiposity probably contributed significantly, but additional mechanisms may also be involved, such as improved insulin sensitivity, reduced inflammation, reduced aromatization for the adipose tissue, and potentially a restoration or improvement of the hypothalamic-pituitary-gonadal axis," he noted