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Some examples of diseases that creatine may prevent or treat are diabetes, cardiovascular disease, osteoporosis, Alzheimers disease, Parkinsons disease, and depression

[6] Children in some regions of developing countries are at particular risk due to increased requirements during growth coupled with diets low in animal-sourced foods

it helps to focus on reactions that are known to be key regulators of the overall pathway flux (bottlenecks), those close to connection points to other pathways, and those with the most complicated mechanisms

Minimizing them requires understanding what they are, why they happen, and how to manage each one