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Dec 29, 2025 Cagrilintide is a long-acting amylin receptor agonist that produces 10-12% body weight loss through mechanisms completely different from GLP-1s - dramatically slowing gastric emptying, suppressing appetite via brain amylin receptors, and reducing postprandial glucose
They mimic the hormone GLP-1 mentioned above
They proposed that bystander activation might be achieved through the following ways: by provoking cell death and thus the release of cellular antigens, increasing the visibility or abundance of antigens
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