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It works in a similar way to injectable GLP-1 receptor agonists like Wegovy and Mounjaro, but in a pill form that does not require refrigeration or needles

When deficiencies are identified through blood testing, supplementing those specific nutrients has good evidence for benefit

Exposures New users of GLP-1RA were separately compared with new users of dipeptidyl peptidase-4 inhibitors (DPP4i) and sodium-glucose cotransporter 2 inhibitors (SGLT2i), using 1:1 propensity score matching to adjust for differences in patient characteristics

The compound exerts dual benefits in neuropathic mice, normalizing depression-like behaviors through supraspinal serotonergic modulation (enhancing 5-HT signaling) and GABAA receptor activation while simultaneously reducing neuropathic pain symptoms (Zhao et al., 2014)