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During pulldown experiments to identify TG2-interacting proteins and to analyze domaindomain interactions, lysates from cells that express a high level of TG2 exhibited an increase in aggregate formation

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Triple agonist mechanism explained Three receptor targets: Retatrutide activates GLP-1 receptors responsible for appetite suppression, insulin secretion enhancement, and gastric emptying delay, similar to semaglutide and other GLP-1 agonists