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MAPKs, including extracellular signal-regulated kinases (ERK), c-Jun N-terminal kinases (JNK), and p38 MAPKs, regulate various cellular activities such as growth, differentiation, and apoptosis

These findings suggest that curcumin can regulate the differentiation and function of Breg cell to alleviate DSS-induced colitis mice, which may be realized by inhibiting TLR/MyD88 pathway

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