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J Clin Invest 1967;46:195462

Plans could see real savings, Fendrick said, if they covered GLP-1s for initial weight loss then moved people to cheaper options -- such as more affordable drugs or behavioral health programs -- to maintain it

Although the mechanisms leading to a blood pressure decrease during the treatment with GLP-1 agonists have not been fully elucidated it could be the result of an increased sodium and water excretion and/or inhibition of the RAAS activity 14

However, it has been shown that GLP-1 secretion in response to mixed nutrient (carbohydrates, fats and proteins) intake is much higher than that secreted after glucose ingestion