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Neurogastroenterol Motil 32(2):e13738

This observation sparked interest in developing medications that could boost incretin activity, potentially treating both diabetes and obesity

Second, a reduction in tubular reabsorption of both free carnitine and acylcarnitine has been reported during VPA treatment [45, 46], Third, VPA reduces endogenous synthesis of carnitine by blockade of the enzyme butyrobetaine hydroxylase