Common and potential side effects include: Skin irritation : Redness, itching, rashes, or allergic reactions where the patch sits, especially with daily use Cardiovascular effects : Bitter orange extract can increase heart rate and blood pressure Digestive issues : Green tea extract may cause upset stomach or headaches Sleep problems : Caffeine content from green tea extract can disrupt sleep Liver concerns : Garcinia cambogia has been linked to liver problems in some cases Unknown risks : Lack of regulation means uncertain ingredient quality and quantities The bigger concern is that these products arent regulated in the same way as prescription medications
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Disclosures: Robin Kate Kelley: Astra Zeneca: Grant/Research Support, Bayer: Grant/Research Support, Eli Lilly: Grant/Research Support, Exelixis: Grant/Research Support, Genentech/Roche: Grant/Research Support, Kinnate: Consultant, Merck: Grant/Research Support, Partner Therapeutics: Grant/Research Support, Regeneron: Consultant, Agios: Grant/Research Support, BMS: Grant/Research Support, QED: Grant/Research Support, Tyra: Grant/Research Support, Taiho: Grant/Research Support, Surface: Grant/Research Support, Servier: Grant/Research Support, GSK: Consultant, moderna: Consultant, J Pharma Inc.: Consultant, Relay Therapeutics: Grant/Research Support, Young Lee: AstraZeneca PLC: Employee, AstraZeneca PLC: Stock - publicly traded company, James Conway: Nothing to Disclose, John Kurland: Nothing to Disclose, Alejandra Negro: Nothing to Disclose, Patricia McCoon: AstraZeneca: Employee 1832 EMERALD-Y90: A PHASE 2 STUDY TO EVALUATE TRANSARTERIAL RADIOEMBOLIZATION (TARE) FOLLOWED BY DURVALUMAB (D) AND BEVACIZUMAB (B) FOR THE TREATMENT OF PARTICIPANTS (PTS) WITH UNRESECTABLE HEPATOCELLULAR CARCINOMA (UHCC) ELIGIBLE FOR EMBOLIZATION Riad Salem 1 Anne Noonan 2 Ben Spieler 3 Sarah White 4 Laura Kulik 5 Dex Underwood 6 Eric Heilbron 6 Binh Nguyen 6 Graham Wetherill 7 Renuka Iyer 8 , 1 Northwestern University, Chicago, IL, USA, 2 The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA, 3 University of Miami, Miami, FL, USA, 4 Medical College of Wisconsin, Milwaukee, WI, USA, 5 Northwestern Memorial Hospital, Chicago, IL, USA, 6 AstraZeneca, Gaithersburg, MD, USA, 7 AstraZeneca, Cambridge, UK, 8 Roswell Park Cancer Institute, Buffalo, NY, USA Background: Intermediate HCC is often treated with locoregional therapy (LRT), such as transarterial chemoembolization (TACE) or TARE

The provider reviews medication dosing and how long the patient has been taking the drug