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VILNIUS, Lithuania, April 28, 2026 (GLOBE NEWSWIRE) -- For many adults, weight management doesn't feel like a simple equation of diet and discipline

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Lipodystrophy Administration of insulin, including NOVOLOG, subcutaneously and via subcutaneous insulin infusion by external pump, has resulted in lipoatrophy (depression in the skin) or lipohypertrophy (enlargement or thickening of tissue) in some patients [see Dosage and Administration (2.2)]

While a few non-electrophilic, non-covalent TRPA1 activators are reported (e.g., carvacrol) 4 , only one (PF-4840154) is especially potent 22