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Supplementation may be most relevant for individuals with documented oxidative stress, certain genetic polymorphisms affecting glutathione metabolism, or conditions like autoimmune disease or chronic fatigue where antioxidant support is clinically considered

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Unlike enrolling in a formal clinical trial (which has extensive consent forms explaining experimental status), patients at wellness clinics might assume if a doctor offered it, it must be safe or allowed. Such misunderstandings could lead to feelings of betrayal and litigation if things go wrong