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Disulfide bonds between cysteine residues in peptide chains contribute to the 3D structure of proteins

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Sequencing libraries were prepared using the NEBNext UltraExpress RNA Library Prep Kit for Illumina (NEB, E3330) according to the manufacturer protocol and sequenced on DNBSEQ-G400, MGI (150 bp paired-end, minimum 100 mil reads per condition, 2 biological replicates)

The microbiota toxic substances lead to macrophage activation in the Kupffer cells, the livers resident macrophages, become activated by LPS and other microbial products, producing ROS and pro-inflammatory cytokines