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When Vitamin D levels drop, multiple systems begin to weaken simultaneously

For instance, a case series involving 12 women with interstitial cystitis reported symptom improvement after bladder-wall injections of BPC-157, yet the study lacked placebo controls, long-term follow-up, and was published in a non-indexed, alternative medicine journal

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These deficits are mediated by EC senescence and inhibited activation of endothelial nitric oxide synthase (eNOS), which is exacerbated by the internalization of soluble tau [196]