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Prescription alternatives to semaglutide include tirzepatide, liraglutide, bupropion/naltrexone (Contrave), phentermine/topiramate (Qsymia), orlistat, oral semaglutide (Rybelsus), dulaglutide, and exenatide

According to Duah, Dexterity and vision can also play a role in a persons comfort with using a pen, and people with issues in those realms may want to opt to take a pill. Alternatively, Duah noted, If the patient already suffers from gastrointestinal issues like nausea, heartburn, diarrhea, or constipation, [licensed physicians] would [consider] injected Victoza or Ozempic over oral Rybelsus as the oral formulation has a higher risk of side effects. While Rybelsus is an effective treatment for type 2 diabetes, its not suitable for everyone

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Bupropion-naltrexone (Contrave) Contrave combines an antidepressant (bupropion) with an opioid antagonist (naltrexone) to target reward-based eating behaviors