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However, because inositol enhances insulin sensitivity and semaglutide increases insulin secretion, blood glucose monitoring becomes important to detect hypoglycemic risk, particularly in patients with type 2 diabetes

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FARXIGA 10 mg as monotherapy also provided statistically significant improvements in FPG and statistically significant reduction in body weight compared with metformin alone and was non inferior to metformin XR monotherapy in lowering HbA1c Figure 2: Adjusted Mean Change from Baseline Over Time in HbA1c (%) in a 24-Week Active-Controlled Trial of FARXIGA Initial Combination Therapy with Metformin XR In a second trial (NCT00643851), 603 patients were randomized to 1 of 3 treatment arms following a 1-week lead-in period: FARXIGA 5 mg plus metformin XR (up to 2,000 mg per day), FARXIGA 5 mg plus placebo, or metformin XR (up to 2,000 mg per day) plus placebo