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Cardiovascular outcomes also improved in non-diabetic users: reductions in blood pressure, improved cholesterol profiles, and decreased inflammation markers appeared regardless of baseline glucose levels

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Third, it upregulates VEGFR2 and activates the VEGFR2-Akt-eNOS pathway, accelerating blood vessel formation and blood flow recovery in ischaemic tissue, a mechanism confirmed in endothelial cell culture and rat hind-limb ischaemia models by Hsieh 2017

L., Li, Y., & Lu, H