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Vitamin B12 blood levels and peripheral blood counts must be monitored initially at one month after the start of treatment with Nascobal Nasal Spray, and then at intervals of 3 to 6 months

peak plasma levels of urolithin A and its metabolites only reach about 110 ng/mL (equivalent to 1.2 M) even after direct supplementation with 500 mg of urolithin A in healthy adults (28)