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The corresponding therapeutic interventions can further increase ROS levels, potentially exceeding the threshold for cell death in tumor cells

We know that uncontrolled redox reactions of copper that can be deleterious to life [12, 65,66,67,68,69,70,71,72,73,74,75], however, here we focus on and re-consider the controlled, redox capability-related signalling of copper that may be important for neurobiology

These findings suggest that fumarase insufficiency in SS rats might contribute to the predisposition to developing salt-sensitive hypertension by decreasing NO and increasing H 2 O 2 in the kidneys (Fig

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