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The decreases in feeding behavior are associated with declines in the expression and release of NPY and AgRP in the hypothalamus

High-fiber foods that support GLP-1 production include: Legumes and pulses : Lentils, chickpeas, black beans, and kidney beans provide both soluble fiber and resistant starch Whole grains : Oats, barley, quinoa, and intact whole grains (not refined products) Vegetables : Particularly cruciferous vegetables (broccoli, Brussels sprouts), artichokes, and leafy greens Nuts and seeds : Almonds, chia seeds, flaxseeds, and psyllium husk Fruits : Berries, apples with skin, pears, and citrus fruits The USDA Dietary Guidelines for Americans recommend consuming 14g of fiber per 1,000 calories, which translates to about 25g daily for women and 38g for men

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The CONSORT diagram reporting disposition for all 110 enroled participants is shown in Extended Data Fig