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According to the pathogenicity criteria from the American College of Medical Genetics and Genomics, the variants can be classified as pathogenic, likely pathogenic, benign, likely benign, or VUS [85], based on criteria using population, computational, functional data, and segregation data

The post says patients on immunosuppressive medications including 5-ASAs, azathioprine and biologics such as infliximab can generally use GLP-1 medications concurrently, though each combination warrants provider review

The 7.5% threshold used to be 10%, but legislative changes at the end of 2019 lowered it

Real-world trends in GLP-1 treatment persistence and prescribing for weight management.