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Islets were purified using an Optiprep gradient (Nycomed, Oslo, Norway) as previously described 81 and cultured for 18 h in a 37 C in a 5% CO 2 incubator in Roswell Park Memorial Institute (RPMI) medium supplemented with 10% heat-inactivated fetal bovine serum before use in experiments

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The improvements in employment rates and work productivity across both absenteeism and presenteeism suggest that treatment with bimekizumab may allow patients living with PsA to reenter the employment market, indicating reduced burden of disease in individuals with a desire to return to work

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