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Its primary application lies in serving as a diluent, making it crucial in preparing and administering various medications

[27] Vitamin B 12 deficiency has the potential to influence methylation patterns in DNA, besides other epigenetic modulators such as micro (RNAs), leading to the altered expression of genes

ARBs and target organ protection

Histone deacetylases (HDACs) are recognized for their role in the transcriptional regulation of proinflammatory genes, and their inhibitors are commonly utilized to treat RA pathogenesis [33]