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Safe B12 Dosage and NHS Recommendations The NHS and UK health authorities provide clear guidance on appropriate vitamin B12 intake, emphasising that most people obtain sufficient amounts through diet alone

The medication's formulation is slightly alkaline compared to the skin's natural pH, which may cause transient irritation of subcutaneous tissues and nerve endings

B12 injection shots can usually be felt within 24 hours (and a change should show in blood tests after a month or two) A high dose of B12 oral supplementation takes the same time as an injection: roughly 24 hours to feel an improvement and then up to 2 months to show in blood markers