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Heres a list of potential causes: Smoking and vaping Sun exposure Drinking from a straw or bottle Repeated facial expressions Pouting/smiling Playing musical instruments (like the recorder or harmonica) Genetics Lifestyle factors Among these, smoking, including vaping, is one of the primary factors leading to vertical, fine lines and wrinkles appearing around the mouth

(16) (17) In addition to the physical effects of asbestos-related diseases, victims may experience fear, stress, anxiety, and depression

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Smoking may predispose to depression and, conversely, may be an antecedent to smoking, in the adolescent population (Brook et al., 2004