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The sample size was based on the principle of data saturation 24 , seeing saturation when new data collected repeats what was expressed in the previously collected data 25

Cigarette smoking (CS) is a well-established risk factor for a wide range of systemic diseases, including cardiovascular disorders, respiratory diseases, diabetes, inflammatory bowel diseases, and various cancers [4, 5]

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In the Philippines, PMI has operated a tobacco leaf warehouse in the Subic Bay Free Port Zone (since at least 2009) and a manufacturing facility in the First Philippines Industrial Park