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PMCID: PMC3910051 14 Smoking and health

Finally, Wendy Burn (from Equally Well) and Simon Gilbody (from the Closing The Gap Network) provided brief reflections on the morning and suggested ways to take this important work forwards

What it looks like The classic tuberculous ulcer has a few recognisable features: A single chronic ulcer, often on the mid-dorsum (top surface) of the tongue , but sometimes on the palate, lip, gum, or buccal mucosa An angular, stellate (star-shaped), or irregular outline rather than a clean round shape Overhanging, undermined edges and a pale, granular floor Surrounding tissue that feels firm or indurated (firm and unyielding) when pressed Size ranging from about one to five centimetres A grey-yellow exudate may cover the surface Other presentations described in the books include non-healing extraction sockets, areas of granular inflammation on the gum, swellings of the jaw, and enlarged neck lymph nodes that may eventually break down through the skin (a presentation called scrofula)

PMID: 37166415 5 Identification of Factor XIII -Sandwich Residues Mediating Glutamine Substrate Binding and Activation Peptide Cleavage