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In the brain, nicotine works mostly to release other neurotransmitterslike dopamine (pleasure), norepinephrine (arousal and appetite suppression), glutamate (learning and memory), endogenous opiates, and serotonin (mood modulation)

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Unlike ordinary household odors, smoke particles penetrate porous materials such as carpeting, upholstery, drywall, insulation, wood, and fabrics