Exposure to SHS alters the immune mechanisms during allergic diseases
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First, chronic inflammationprimarily mediated by neutrophils and macrophagesdirectly damages the epithelium and extracellular matrix (ECM) through proteases (e.g., MMPs, elastase), chemokines, and reactive oxygen species, thereby promoting structural destruction and airway narrowing
La nicotine supprime la sensation de manque et permet ainsi de limiter le grignotage pour compenser les envies de fumer