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It is possible that the tar, nicotine, and carbon monoxide in cigarette smoke 40 activate ILC3s by binding to toll-like receptors and aryl hydrocarbon receptors 41

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Below is more information about it via a news release from NORML: South Brisbane, Australia: The long-term inhalation of cannabis smoke does not impact lung function in the same manner as inhaling tobacco, according to longitudinal data published in the journal Respiratory Medicine